I. Granulation Feeding
Device:
In many cases, speed of die
table is such that the time of die under feed frame is too short to allow
adequate or consistent gravity filling of die with granules, resulting in
weight variation and content uniformity. These also seen with poorly flowing granules.
To avoid these problems, mechanized feeder can employ to force granules into
die cavity.
II. Tablet weight monitoring
devices:
High rate of tablet output with
modern press requires continuous tablet weight monitoring with electronic
monitoring devices like Thomas Tablet
Sentinel, Pharmakontroll and Killan control System-MC. They
monitors force at each compression station by starin gage technology which is then
correlated with tablet weight.
III. Tablet De-duster:
In almost all cases, tablets
coming out of a tablet machine bear excess powder on its surface and are run
through the tablet de-duster to remove that excess powder.
IV. Fette machine
Fette machine is device that
chills the compression components to allow the compression of low melting point
substance such as waxes and thereby making it possible to compress product with
low meting points.
Packaging
Pharmaceutical manufacturers
have to pack their medicines before they can be sent out for distribution. The
type of packaging will depend on the formulation of the medicine.
'Blister packs' are a common
form of packaging used for a wide variety of products. They are safe and easy
to use and they allow the consumer to see the contents without opening the
pack.
Many pharmaceutical
companies use a standard size of blister pack.
This saves the cost of
different tools and to change the production machinery between products.
Sometimes the pack may be perforated so that individual tablets can be
detached.
This means that the expiry
date and the name of the product have to be printed on each part of the
package. The blister pack itself must remain absolutely flat as it travels
through the packaging processes, especially when it is inserted into a carton.
This poses interesting
problems for the designers. Extra ribs are added to the blister pack to improve
its stiffness.
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