Standardization of 1 Molar Sodium Hydroxide solution

 

Standardization of 1 Molar Sodium Hydroxide solution

Standardization of 1 Molar Sodium Hydroxide solution

¨  Crush slightly and then accurately weigh about 5 gram (5000mg) of Potassium biphthalate.

¨  Dried at 120◦C for 2 hours in an oven.

¨  Dissolve in 75ml carbon-dioxide free water.

¨  Add 2 drops of phenophthalein indicator.

¨  Titrate with 1 molar Sodium Hydroxide solution with constant stirring till a permanent Pink color is produced.

¨  Each ml of 1 molar sodium hydroxide solution is equal to 204.22 mg of Potassium biphthalate.

¨  Molarity =                weight of potassium biphthalate taken(mg)

                             molecular weight of potassium biphthalate x ml of 1 M NaOH used

¨  Molarity=  weight of potassium biphthalate taken(mg)

                                        204.22 x ml of 1 M HCl used

Note

¨  Standardization is only required when the solution is used for quantitative analysis.

¨  In case of qualitative analysis such as pH adjustment, dissolution medium or diluent there is no need of standardization.

 Presented By

Muhammad Atif

PhD Scholar Pharmaceutical Sciences

Abdul Wali Khan University Mardan, Pakistan